Polyvinylpolypyrrolidone CAS 9003-39-8 Crospovidone (PVP-P)
■ Chemical Description
--Polyvinylpolypyrrolidone (abbr. PVP-P)
■ CAS No. 9003-39-8
■ INCI Name Crosslinked PVP
■ Molecular and Structural Formula (C6H9NO)n
■ Characteristics
--A white to yellowish white, hygroscopic powder;
--Practically insoluble in water and other common solvents
--Disintegrant for tablets, granules and hard gelatin capsules;
--Stabilizer for oral and topical suspensions;
--Improvement of dissolution and bioavailability, Filtration aid
--Packed in 20 kg fiber or plastic drum, inner lined with PE bags;
--Stored in dry place at room temperature
No |
Tests |
Specification |
1 |
Identification, A B C D |
Complies |
2 |
Peroxides(as H2O2),ppm |
≤400 |
3 |
Water-soluble substances,% |
≤1.0 |
4 |
Impurity A (1-vinylpyrrolidone-2-one),ppm |
≤10 |
5 |
Heavy metals, ppm |
≤10 |
6 |
Loss on drying,% |
≤5.0 |
7 |
Sulphated ash % |
≤0.1 |
8 |
Assay, % |
11.0-12.8 |
9 |
Average Particle size, Type A, um |
100 |
10 |
Average Particle size, Type B, um |
30 |
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