Tus nqi zoo tshuaj intermediates 99% Nicergoline CAS 27848-84-6
Tus nqi zoo tshuaj intermediates 99% Nicergoline CAS 27848-84-6
Cov ntsiab lus khoom:
Lub Npe Tshuaj: Nicergoline
Cov mis molecular: C24H26BrN3O3
CAS Naj Npawb: 27848-84-6
Qib: CP/EP/USP
Kev Taw Qhia:
Nicergoline, zoo li Sermion, Joseph Hermione, nicergoline, Kell; koj yeej thawj ninni cabergoline tshuaj hu ua alpha 10 methoxy ob methyl -1,6- cabergoline -8 beta 5''- nicotinate. Bromine methanol raws li molecular formula: c24h26brn3o3 molecular hnyav yog 484.39. lossis cov cim qhia mob hnyav mob hlwb lossis mob hlwb metabolic dysfunction. Kev txav mus los, mob hlwb tsis zoo los ntawm kev hais lus tsis meej, kiv taub hau, tinnitus, pom kev tsis meej, kev xav, mob taub hau, pw tsis tsaug zog, nco tsis tau, tsis mloog zoo, kev nyuaj siab, kev ntxhov siab, kev zoo siab thiab kev puas hlwb. Nicergoline ntsiav tshuaj yuav txhim kho cov ntshav siab txo cov tshuaj ua haujlwm. Vim yog nicergoline metabolized los ntawm CytochromeP4502D6, tsis tshem tawm kev sib cuam tshuam nrog cov tshuaj los ntawm tib txoj kev.
Cov Haujlwm:
1. Nicergoline yog ib qho ergot derivative siv los kho senile dementia thiab lwm yam kab mob uas muaj keeb kwm vascular.
2. Nws tau pom tias ua rau lub hlwb muaj zog dua thiab ua rau pom tseeb dua.
3. Nws txo cov hlab ntsha tsis kam thiab ua rau cov ntshav ntws hauv lub hlwb ntau ntxiv, txhim kho kev siv oxygen thiab qabzib los ntawm cov hlwb hlwb.
4. Nws muaj cov khoom zoo sib xws rau lwm qhov ntawm lub cev, tshwj xeeb tshaj yog lub ntsws.
5. Nws yog siv rau cov kab mob vascular xws li cerebral thrombosis thiab atherosclerosis, arterial blockages hauv ob txhais ceg, Raynaud's kab mob, vascular migraines, thiab retinopathy.
6. Nicergoline tau raug sau npe hauv ntau tshaj tsib caug lub tebchaws thiab tau siv ntau tshaj peb caug xyoo rau kev kho mob ntawm kev xav, kev xav, thiab kev coj cwj pwm ntawm cov neeg laus.
Ntim:
lub hnab yas sab hauv thiab lub hnab txhuas sab nraud
Cia: Nyob rau hauv qhov ntxoov ntxoo ntawm qhov tsaus ntuj thiab qhov xwm txheej. Thiab qis kub (+ 2-- + 8ºC)
| YAM KHOOM | INDEX |
| Cov yam ntxwv | Dawb siv lead ua los yog hmoov |
| Qhov kub yaj | 133ºC ~ 136ºC |
| Kev tig kho qhov muag tshwj xeeb | Ua raws li |
| Kev meej thiab xim ntawm cov tshuaj | Ntshiab |
| Cov khoom muaj feem xyuam | Tag nrho cov khoom tsis huv ≤1.5% Nor-nocergoline (B) ≤0.50% Chioronicergoline (A) ≤0.5% MeLUOL (C) ≤0.30% Tsis paub meej txog qhov tsis huv: ≤0.30% |
| Dej | ≤0.5% |
| Hlau hnyav | ≤20ppm |
| Cov seem ntawm kev hlawv | ≤0.05% |
| Kev Ntsuas | 98.5% ~ 102% |
| Cov tshuaj yaj seem | |
| Acetone | ≤1000ppm |
| Diethyl ether | ≤2000ppm |
| Ethanol | ≤1000ppm |
| Methanol | ≤1000ppm |
| Toluene | ≤500ppm |
| Dichloromethane | ≤100ppm |
| Triethylamine | ≤500ppm |
| Xaus lus | Ua raws li EP 5.0 |
| * Ntxiv rau: Lub tuam txhab tuaj yeem tshawb nrhiav thiab tsim cov khoom tshiab raws li qhov xav tau tshwj xeeb ntawm peb cov neeg siv khoom. | |
