Ixabiso elihle Iingcali zeMithi eziPhakathi 99% iNicergoline CAS 27848-84-6
Ixabiso elihle Iingcali zeMithi eziPhakathi 99% iNicergoline CAS 27848-84-6
Iinkcukacha zemveliso:
Igama leKhemikhali: iNicergoline
Ifomula yeMolekyuli：C24H26BrN3O3
Inombolo ye-CAS: 27848-84-6
Ibanga: CP/EP/USP
Intshayelelo:
I-Nicergoline, njengoSermion, uJoseph Hermione, i-nicergoline, uKell; uphumelele ikhemikhali yokuqala ye-ninni cabergoline ebizwa ngokuba yi-alpha 10 methoxy two methyl -1,6- cabergoline -8 beta 5''- nicotinate. Ifomula yemolekyuli esekwe kwi-Bromine methanol: c24h26brn3o3 ubunzima bemolekyuli yi-484.39. okanye iimpawu ezibukhali Ukuphazamiseka kwe-cerebrovascular okungapheliyo okanye ukungasebenzi kakuhle kwe-metabolic yobuchopho. Ukuhambahamba, ukungasebenzi kakuhle kwengqondo okungapheliyo okubangelwa yimiqobo yolwimi, isiyezi, i-tinnitus, umbono ofipheleyo, imvakalelo, intloko ebuhlungu, ukungalali, ukulahleka kwenkumbulo, ukungakhathali, ukudakumba, ixhala, uvuyo kunye ne-dementia. Iipilisi ze-Nicergoline zinokuphucula umsebenzi wamayeza okunciphisa uxinzelelo lwegazi. Ngenxa yokuba i-nicergoline inyibilikiswa yi-CytochromeP4502D6, ayikhuphi ngaphandle ukusebenzisana namayeza ngendlela efanayo.
Imisebenzi:
1. I-Nicergoline sisithako esisetyenziswa kwi-ergot esetyenziselwa ukunyanga i-senile dementia kunye nezinye iingxaki ezinemvelaphi yemithambo yegazi.
2. Kufunyenwe ukuba kwandisa ubuchule bengqondo nokuphucula ukucaca nokuqonda.
3. Inciphisa ukumelana nemithambo yegazi kwaye inyusa ukuhamba kwegazi kwimithambo yegazi engqondweni, iphucula ukusetyenziswa kweoksijini kunye neglucose ziiseli zengqondo.
4. Ineempawu ezifanayo zokukhupha igazi kwezinye iindawo zomzimba, ingakumbi imiphunga.
5. Isetyenziselwa iingxaki zemithambo yegazi ezifana ne-cerebral thrombosis kunye ne-atherosclerosis, ukuvaleka kwemithambo yegazi emalungeni, isifo sikaRaynaud, i-vascular migraines, kunye ne-retinopathy.
6. I-Nicergoline ibhalisiwe kumazwe angaphezu kwamashumi amahlanu kwaye isetyenzisiwe kangangeminyaka engaphezu kwamashumi amathathu kunyango lweengxaki zengqondo, iimvakalelo, kunye nokuziphatha kwabantu abadala.
Ukupakisha:
ingxowa yeplastiki ngaphakathi kunye nengxowa ye-aluminium ngaphandle
Indawo yokugcina: Emthunzini omnyama naphantsi. Kunye nobushushu obuphantsi (+2--+8ºC)
| INTO | ISALATHISO |
| Iimpawu | Ikristale emhlophe okanye umgubo |
| Indawo yokunyibilika | 133ºC ~ 136ºC |
| Ukujikeleza okubonakalayo okuthe ngqo | Ukuhambelana |
| Ukucaca kunye nombala wesisombululo | Cacisa |
| Izinto ezinxulumene noko | Ukungcola okupheleleyo ≤1.5% I-Nor-nocergoline (B) ≤0.50% I-Chioronicergoline (A) ≤0.5% I-MeLUOL (C) ≤0.30% Ukungcola okungaziwayo: ≤0.30% |
| Amanzi | ≤0.5% |
| Intsimbi enzima | ≤20ppm |
| Intsalela ekutshisweni | ≤0.05% |
| Uvavanyo | 98.5% ~ 102% |
| Izinyibilikisi ezisele | |
| I-acetone | ≤1000ppm |
| I-ether yeDiethyl | ≤2000ppm |
| I-Ethanol | ≤1000ppm |
| I-Methanol | ≤1000ppm |
| IToluene | ≤500ppm |
| I-Dichloromethan | ≤100ppm |
| I-Triethylamine | ≤500ppm |
| Isiphelo | Vumelana ne-EP 5.0 |
| * Ukongeza: Inkampani ingaphanda kwaye iphuhlise iimveliso ezintsha ngokwemfuno ekhethekileyo yabathengi bethu. | |
